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More practical contributors to heart rate increases, especially early in therapy, may include volume depletion from gastrointestinal side effects such as nausea, vomiting, and diarrhea, which are common during GLP-1 receptor agonist initiation

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Jensen MH, Kjolby M, Hejlesen O, et al

Avoid using L-Carnitine if you have a history of seizures or epilepsy, as it may lower the seizure threshold

This rate of synthesis, combined with efficient (95%) L-carnitine reabsorption by the kidneys, is sufficient to prevent deficiency in generally healthy people, including strict vegetarians (132)

Did they worsen, improve, or stay the same