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GLP-1 Medications & Diet
The next phase of GLP-1 development will no longer be defined by companies capability to develop the drug but their ability to develop systems that can consistently and reliably produce them at scale
At baseline, 95% of patients were treated with an ACE inhibitor or ARB, 16% were on SGLT-2is, 76% were on a statin, and 50% were on an antiplatelet agent
This is the process by which insurance providers determine whether a certain drug or brand is truly necessary, and it may include step therapy, which involves trying lower-cost medications before moving on to Ozempic
In the larger SELECT trial in 2023, patients with heart failure, atherosclerotic disease, and overweight or obesity, treated with semaglutide 2.4 mg showed reduction in major adverse cardiac events (MACE) and heart failure end points regardless of heart failure subgroup being HFrEF or HFpEF [56,57,58]
According to the WHO report, this was based on emerging global safety signals and case reports
