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The main cause of Reyes syndrome appears to be the accumulation of nonesterified fatty acids and lysolecithins that have a high detergent activity and thus denature all proteins

To examine the incorporation of GSH-derived cysteine into downstream pathways, we used an inverse stable-isotope labelling approach 34,35

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10.1016/j.arcmed.2014.11.018 Arch

91 In essence, long-acting formulations can achieve sustained therapeutic drug concentrations in the body, whereas short-acting formulations produce transient concentration peaks shortly after injection