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There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision

Eli Lilly has just released the latest positive Phase III trial results of its experimental oral GLP-1 drug, orforglipron

Reason being, a large portion of these effects are through appetite suppression

Its important to point out a few things first

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