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Orthop Res 2003;21:976983
Combining a GLP-1 receptor agonist with a DPP-4 inhibitor is not recommended because both work through the incretin system, and the additional glucose-lowering benefit of using both together is modest
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For people who meet clinical BMI criteria, have tried sustained diet and exercise without lasting results, and lack insurance coverage for FDA-approved GLP-1s, Yucca Health's compounded options may represent a financially accessible path to medications that clinical evidence suggests can support meaningful weight loss alongside lifestyle changes
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Mounjaro is FDA-approved to treat type 2 diabetes alongside diet and exercise
