Lanthionine GSG in turn, forms an irreversible mixed disulfide with protein thiols that could lead to dysregulation of proteins that are normally regulated by reversible glutathionylation 81
& Rogers, P
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Ongoing studies continue to examine its potential role in telomerase regulation, telomere maintenance, genomic stability, cellular senescence, oxidative stress, and circadian physiology
In fact, our previous study showed that changes in Bdnf expression could be successfully evaluated by measuring luciferase activity as well as a bioluminescence signal in cultured cortical cells 19,20