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Here, we have used a novel 2 H MRS method, referred to as deuterium MRS (DMRS) [23], which has the potential for broad application in in vivo studies to assess brain metabolism and activity in preclinical and clinical settings

At 5 mg/ml, a single 5 mg vial holds 20 initiation doses

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These standards were subjected to the same sample preparation protocol mentioned earlier, followed by the LC-MS analysis