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James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O (2009) Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism
202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione
Even when a compounded product exists, it is not FDA approved
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This gastric emptying effect is most pronounced early in treatment and may diminish with ongoing therapy