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NNMT Inhibition and Intracellular Signaling The primary mechanism of 5-AMINO-1MQ 10MG involves the potent, selective inhibition of the NNMT enzyme, which is often overexpressed in metabolic disorders

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This assay utilized recombinant human CSNK1A1 and peptides corresponding to the hinge region of NHR-49 as the substrate to test for direct phosphorylation