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L-carnitine is a cellular compound essential for human health
It is a hallmark of metabolic health and reflects adaptive fuel utilization
In the STEP and SURMOUNT trials: Constipation was reported in up to 24% of patients on semaglutide 18-23% of patients on tirzepatide experienced constipation It is one of the top three side effects of these medications and is more frequent in those who: Lose weight rapidly Eat low-fiber diets Are female (due to hormonal factors affecting gut motility) Conventional Treatment Approaches Most providers recommend over-the-counter (OTC) remedies such as: Stool softeners (docusate) Fiber supplements (psyllium, methylcellulose) Laxatives (PEG 3350, senna, Mag Citrate) These can help in the short term but do not address the root cause
Vitamin B12 and iron are needed for healthy blood cell function, and deficiencies can lead to anemia, a condition characterized by ineffective transport of oxygen to cells and tissues
If you experience any of these, stop the medication and contact your healthcare provider immediately
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