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Sudden chest pain, shortness of breath, or one-sided leg swelling should not be treated as routine soreness

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Cook SF, King AD, van den Anker JN et al , Simultaneous quantification of acetaminophen and five acetaminophen metabolites in human plasma and urine by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry: method validation and application to a neonatal pharmacokinetic study

For providers who have built a structured, relationship-based practice, this is a meaningful distinction and one worth making explicit with patients who ask about lower-cost alternatives

doi: 10.3390/su13052856 46 HartM.EhretD