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Unless you have a diagnosed vitamin or mineral deficiency, nutritional needs are best met with food, not supplements

Clinical and pharmacological differences in early- versus late-onset Parkinsons disease

The primary mechanism involves intrinsic factor binding in the stomach, while a secondary pathway allows small amounts to absorb through passive diffusion

Oral B12 relies on gut absorption, which is fine for mild low intake but not ideal if a gut condition, a medication, or age is limiting absorption

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Long-term safety in injectable use is not well characterized in published trials