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But the strongest results came from retrospective analyses with major potential for residual confounding, and the signal weakened in the comparison against SGLT2 inhibitors
Efficacy of dulaglutide on vascular health indexes in subjects with type 2 diabetes: a randomized trial
The SUSTAIN-6 trial for semaglutide (3,297 patients, median 2.1 years), LEADER trial for liraglutide (9,340 patients, median 3.8 years), and REWIND trial for dulaglutide (9,901 patients, median 5.4 years) all included comprehensive adverse event monitoring
When combined with semaglutide, both can push blood glucose too low, sometimes quickly