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The group receiving a 0.3 mg dose experienced a 6.0% weight loss, with 0.6 mg there was a 6.8% weight loss, with 1.2 mg there was a 9.1% weight loss, with 2.4 mg there was a 9.7% weight loss, and weigh 4.5 mg there was a 10.8% weight loss, compared with 3.0% weight loss for pooled placebo

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Once you grasp that units measure volume and concentration determines potency, the math becomes intuitive

Unpaired t -test

The comparison between berberine and prescription GLP-1 medications reveals fundamental differences in mechanism, potency, evidence base, and regulatory status