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In the N-acetyl form, an acetyl group is added to the N-terminus of the four-residue chain, a modification commonly used in peptide chemistry to alter charge, lipophilicity, and resistance to aminopeptidase activity relative to the unmodified peptide

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Conversely, under specific conditions, glutaredoxins which depend on glutathione for their activity can also reduce oxidized thioredoxins

HernandezAFGreenJBJanmohamedSAgostinoDGrangerRBJonesCBet alAlbiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (harmony outcomes): a double-blind, randomised placebo-controlled trial

Mistro S, Maciel IDM, de Menezes RG, Maia ZP, Schooley RT, Badar R (2012) Does lipid emulsion reduce amphotericin B nephrotoxicity

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