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If you have no real concern for dark spots, or are new to Vitamin C, start with a Vitamin C serum with a lower concentration or one which is formulated with a Vitamin C derivative like Sodium Ascorbyl Phosphate

When produced excessively, it may suppress the release of Thyroid Stimulating Hormone from the pituitary. 18 It also forces T4 to be converted to reverse T3 (rT3) which actually blocks thyroid function, even though thyroxine levels look adequate when tested. 19 Blood glucose imbalance also triggers cortisol secretion, and insulin resistance may have a direct negative effect on the thyroid, too

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doi:10.1016/j.molmet.2018.09.009

Vitamin C directly scavenges free radicals, while glutathione serves a dual role, acting as a direct antioxidant and regenerating other antioxidants, thereby bolstering the overall defense against oxidative damage (25, 30, 31)