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After the drugs were administered to the test subjects for 3 months they underwent the Morris water maze test

Apart from ASPN , RT-qPCR results confirmed higher VCAM1 , HSD3B1 and ESR1 gene expression in HOSC

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A) mice administered Dihexa through a cannula, B) mice administered Dihexa via intraperitoneal injection, and C) mice administered Dihexa via oral delivery methods 2) In order to determine whether AngIV is involved in the development of Alzheimers, the research team of Sun et al detected the baseline levels of AngIV in both wild type and APP/PS1 mice