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Discovery of GLP-1 as a satiety hormone In 1994 I took up the idea with Holst that GLP-1 could also be a mediator of meal-induced satiety, and we designed a study to infuse GLP-1 into normal human volunteers

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Personalized Semaglutide Therapy and Your Individual Risk Your genetic makeup influences how your body responds to semaglutide and how you metabolize alcohol

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It says documented hypoglycemia rates are low in people taking semaglutide without insulin or sulfonylureas, and contrasts that with older glucose-lowering drugs that act regardless of the blood-sugar level at the time