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These treatments dont just promote weight lossthey also improve cardiovascular health, reduce inflammation, and enhance insulin sensitivity

One of the most important drug targets to emerge has been the Glucagon-like peptide-1 (GLP-1) and its receptor (GLP-1R)

[1] [2] This medication works through multiple complementary mechanisms that influence metabolic function throughout treatment

Timmers, S., Schrauwen, P

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NICE Technology Appraisal 875 (TA875) recommends semaglutide for managing weight in adults with obesity within specialist weight management services, typically for people with a BMI 35 kg/m with a weight-related comorbidity, or 30-34.9 kg/m in certain circumstances