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This indicates that due to its ability to move through the blood-brain barrier, DSIP could be beneficially used against sleep disorders due to the similarity between epilepsy and disturbed sleep ( Effects of DSIP on ATP Production DSIP has been linked to different stress-related metabolic disturbances

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Furthermore, phase II studies were undertaken to prove the efficacy of mecasermin rinfabate (IGF-1/IGFBP-3) in paediatric severe burns and had promising outcomes when doses of 14 mg/kg/day [269273] were used