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Key Points Melanomas on the non-glabrous skin (skin outside the palms and soles) can be broadly classified into those that arise on skin with chronic sun-induced damage (CSD melanomas) or those that arise on skin without such damage (non-CSD melanomas)

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Furthermore, NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells that is essential for energy metabolism

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