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Heartburn is a sign that the medication is working in the gut

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Schoneberg, T

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If nausea is severe or persistent (lasting more than a few days after injection), patients should contact their healthcare provider, as dose adjustment or antiemetic medication may be warranted

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If a patient is losing weight while eating more, that points toward hypothyroidism, not the GLP-1 itself

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Whilst these are not caused by GLP-1 medications, they require urgent assessment regardless of current treatment

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