For the research community this means that clinical doses and durations are not validated , most of todays research protocols rely on animal models and hypothetical extrapolations
As energy stabilizes, workouts may feel more manageable and consistency with nutrition often becomes easier
Increased energy and fat-burning
You can use any amount of water, the dosage per unit just decreases
Conversely, if a patient presents with pernicious anemia or severe neurological signssuch as intense tingling in the hands, memory loss, or muscle weaknessthe dosage remains the same (usually 1,000 mcg), but the frequency increases significantly
The NIH factsheet explains that no tolerable upper intake level has been set for B12, because it has a low potential for toxicity in healthy people