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IDH mutation impairs histone demethylation and results in a block to cell differentiation

Whether this decline is a cause or consequence of aging and disease remains an active area of research

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Accessed 5 Jan 2023 Teerlink JR et al (2013) Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

10.1161/CIRCRESAHA.119.316007 64