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Leptin levels decrease during weight loss due to reduced fat mass, which promotes increased food consumption and decreased energy expenditure
Bloomgarden ZT (2025)
Med.Sci Monit
As compared to loop diuretics, SGLT2-i may distinctly regulate the interstitial versus intravascular compartment selectively reducing interstitial oedema, which has been observed in HF and DKD, with minimal change in blood volume
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