Warnings/Cautions: Consult your health professional before use if you are pregnant, breastfeeding, trying to conceive, taking medication, especially anticoagulant drugs such as Warfarin/Coumadin, have a medical condition, or anticipate surgery
Cancer Risk Elevated levels of insulin-like growth factor-1 (IGF-1), which is the downstream effect of GH activity, have also raised theoretical concerns about an increased risk of cancer: According to Roberts, IGF-1 promotes cellular proliferation and inhibits apoptosis, two mechanisms that may contribute to the development of cancer cells in predisposed individuals (22)
S., Alexe, A., Apara, O., et al
Escalation decisions should rely on objective data rather than subjective tolerance alone
This multi-pathway activity resembles what we see with other biologic treatments in orthopedic surgery, where the therapeutic effect comes from coordinated biological response rather than a single drug-receptor interaction
But doctors stress that this isnt a unique issue to either medication