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This copper-peptide complex has been utilized in preclinical studies examining extracellular matrix remodeling mechanisms, collagen and elastin synthesis pathways in isolated cell models, angiogenesis signaling activity, antioxidant enzyme pathway interactions, and stem cell activation dynamics independent of the broader biological effects associated with endogenous copper-peptide complexes

Thus, 1000 g/mL EDTA was used in further stability testing

S5E, F)

Trypsin digestion was diluted with 500 L water, pepsin digestion with 200 L ABC (100 mM)

Prog Neurobiol 94:166200