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[22] [23] Baseline assessment should be considered before initiating tirzepatide in high-risk patients, including those over 65 years of age, individuals with pre-existing gastrointestinal disorders, patients on concurrent metformin or acid-suppressing medications, and those following restrictive diets
Tirzepatide is formulated to mimic the function of native GIP at the GIPR while also interacting with the GLP1R in a manner different from native GLP1
1 Contraindications or require Caution: individuals who are pregnant or breastfeeding, have a history of cancer, or have pre-existing liver or kidney conditions
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Mozzafarian D, Agarwal M, Aggarwal M, et al
A report by Systematix Institutional Equities dated 2 January pegs the generic semaglutide opportunity across India, emerging markets and regulated markets at over 5,000 crore over the next 12-15 months
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