Wang Z, Bergeron N, Levison BS, Li XS, Chiu S, Jia X, Koeth RA, Li L, Wu Y, Tang WHW, et al
Data availability Access to NESDA data used in the present study can be obtained by submitting a research proposal
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however, appetite reduction at 3 months was predictive of 6-month BMI reduction ( Strengths and limitations A strength of this study is our sizable cohort of youth treated in a pediatric weight management clinic over an 8-year period
Its mechanism of action includes stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways
Singh emphasized that the phenomenon appears tied to rapid HbA 1c reduction rather than direct retinal toxicity from the drug itself