Regarding mood and mental health: a review by the EMA's Pharmacovigilance Risk Assessment Committee (PRAC) found no confirmed causal link between GLP-1 receptor agonists and suicidal ideation or self-harm
However, its use in very young children (under six) is generally avoided due to the increased risk of side effects and the lack of robust data on safety and efficacy in this age group
(vi) comorbid diagnosis: Fragile X syndrome, tuberous sclerosis, phenylketonuria or fetal alcohol syndrome or (vii) acute illness
Research is limited on whether microdosing helps maintain weight loss, blood sugar, and the other protective benefits of GLP-1s at standard doses, so experts cant say for certain yet if it works. But more importantly, for someone exploring microdosing for the first time, they might wonder: Is it safe
Yan N, Ricca C, Fletcher J, Glover T, Seizinger BR, Manne V
The answer is simple