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Until more research happens, GLP-1 drugs should only be considered on an individual, case-by-case basis for those with coexisting depression, says Misra
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Best time of day Injectable: Morning administration aligns with natural cortisol rhythms and allows any mild side effects to resolve before sleep
Another hormone released from the gut is GIP
In a 48-week, placebo-controlled phase-2 trial (338 participants) reported by Lilly, the highest dose achieved a mean weight reduction of 24.2% (about 57.8 lb) at the end of treatment
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