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Until such studies are conducted, the combination remains investigational and should be approached with appropriate caution, written informed consent, and consideration of FDA MedWatch reporting for any adverse events that occur with off-label combination use

They upregulate collagen synthesis while inhibiting TGF-, a key factor in androgenetic alopecia

References

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Torres-Ortega PV, Saludas L, Hanafy AS, Garbayo E, Blanco-Prieto MJ

I feel the same as you I have adopted the same type of reasoning with my patients as I try to explain what we know and what we dont know