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doi: 10.1155/2016/2795090 269 TangC.-F.DingH.JiaoR.-Q.WuX.-X.KongL.-D

This age-related decline is one of the most frequently cited data points in copper-peptide research literature, and its a primary reason GHK-Cu is studied within the broader context of cellular aging and peptides for longevity research rather than treated purely as a wound-healing or dermatology compound

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Glutathione and lymphocyte activation: a function of aging and auto-immune disease

[78] [79] The reaction of transition metals with proteins oxidated by reactive oxygen or nitrogen species can yield reactive products that accumulate and contribute to aging and disease