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If replicated in larger prospective trials, that magnitude of difference would carry significant clinical implications

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Parkinson's disease and mitochondrial complex I: a perspective on the Ndi1 therapy

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Methods Eligibility criteria The PICOS strategy was defined as follows: P (participants) human subjects, I (interventions) oral LC treatment, C (comparisons) between supplementation and placebo, supplementation and control, or pre- and post- supplementation, O (outcomes) muscle variables, and S (study design) randomized controlled trials, non-randomized controlled trials, non-randomized non-controlled trials