doi: 10.1523/JNEUROSCI.0567-10.2010 76 SalehNMoutereauSDurrAKrystkowiakPAzulayJ-PTranchantCet al
This level of efficacy is approaching that of bariatric surgery
Patients considering GLP-1 discontinuation should work closely with their healthcare team to develop individualized maintenance plans, establish realistic expectations about weight trajectory, and implement close monitoring for weight regain
Consistent with the results from inflammatory cell infiltration in lung, liraglutide completely reversed up-regulation of TGF-1, IL-1, TNF-, and partially reversed up-regulation of IL-6 mRNA in lung induced by MCT treatment
GLP-1RA also causes apoptosis of CD3 + T cells (Ben et al., 2024), contrary to NK stimulation
These data form the basis of our rolling Biologics License Application (BLA) with the FDA positioning MCO-010 to become the first FDA-approved optogenetic therapy for retinal disease