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The drop-out rate due to adverse events stood at 10.3% for the high-dose group, compared to 7.7% for the 12 mg group, 5.1% for the 6 mg group, and 2.6% for the placebo group

But retatrutide, a triple-receptor agonist targeting GLP-1, GIP, and glucagon simultaneously, delivered weight loss numbers in Phase 3 trials that made researchers rethink what pharmaceutical intervention could achieve

What we are developing could be used as something like maintenance therapy where you could get subcutaneous injections every 3 to 6 months. The market opportunity also resulted in a dramatic legal battle between Pfizer and Novo Nordisk last year, when the two companies fought over buying Metsera, a start-up developing weight-loss drugs

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