GLP-1 receptor agonists have transformed diabetes care, but the long-term safety of GLP-1 therapies has become an important topic as treatment continues for many years
Season with half of the sea salt
GLP-1 receptor agonists are medications that mimic the natural hormone glucagon-like peptide-1 (GLP-1)
According to some publications, the extent and the intensity of physiological oral mucosal melanin hyperpigmentation increase with age probably owing to the cumulative effects of endogenous and extrinsic melanogenic stimuli, such as inflammatory processes, drugs, tobacco smoke, and recurrent minor functional injuries [4, 6, 11, 13]
Comparisons are based on publicly available data as of June 2026
(C, D) Data are mean SEM, analyzed by two-tailed Students t-tests