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In a diabetic kidney disease (DKD) model, liraglutide was demonstrated to enhance renal outcomes through the modulation of gut microbiota composition and the elevation of circulating levels of L-5-Oxoproline (5-OP)
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[11] [12] The most serious but rare adverse effect is lactic acidosis, which occurs primarily in patients with significant renal impairment, acute illness, or conditions causing tissue hypoxia
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