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Selenium, selenoproteins and the thyroid gland: interactions in health and disease
- Tokyo, Japan
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Treatment with selenocystine and ebselen (500 g/kg/day) resulted in significant reduction in ROS production and inhibition of lipid peroxidation, induced GPX4 expression in gastric tissue that induced ulcers in rodent model infected with H
Besides an increased homocysteine export from tissues into plasma that may be regulated by a reduced-homocysteine carrier (Blom, 2000), hyperhomocysteinemia can result from reduced renal function, which may have a central role in plasma homocysteine clearance, and from chronic hepatic insufficiency
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