While Im excited about the potential of GLP-1 drugs, as a medical professional, I also understand the importance of cautious optimism
Who Benefits Most (and Who Doesnt Need It Yet) Strongest Candidates 8+ weeks on GLP-1 with persistent fatigue despite optimized basics Over 40 (NAD+ naturally declines 4050% between ages 4060) Lost 20+ lbs and fatigue worsened with more loss Brain fog that coffee and labs cant explain Workout recovery tanked despite creatine and protein Probably Dont Need It Yet Less than 8 weeks on GLP-1 (still adjusting) Under 35 with mild weight loss goals Fatigue clearly tied to poor sleep, low protein, or dehydration Havent checked basic labs yet (thyroid, iron, D, B12) Energy is fine no fatigue complaint How to Try It (The Practical Guide) Start here: Oral NMN 250mg daily for 14 days
Thomas Clark is Board Certified in Cardiometabolic Medicine and enjoys seeing patients for diabetes management, kidney disease, liver disease, and other chronic conditions
Nutrition and Rest: Proper diet and adequate sleep are fundamental for recovery and performance
Studies on glutathione S-alkyltransferase of the rat
Curcumin, the active ingredient in turmeric, has potent anti-inflammatory properties that can help to reduce inflammation and pain in the body
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