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Expression of DPP-4 is substantially dysregulated in a variety of disease states, including inflammation, cancer, obesity, and diabetes [22]

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Physicians should establish baseline levels of IGF-1, fasting insulin, HbA1c, and a comprehensive metabolic panel prior to initiation

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Im Zentrum steht die blutzuckersenkende Wirkung, die glukoseabhngig erfolgt: Durch die Aktivierung von GLP-1-Rezeptoren auf pankreatischen -Zellen wird die Insulinsekretion nur bei erhhtem Blutzuckerspiegel gesteigert

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