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Early proof-of-concept and phase 2 studies suggested that tirzepatide can improve both markers of beta cell function and insulin sensitivity compared with selective GLP-1 RA therapy [9, 10]

If you have established heart disease and worry about TMAO (trimethylamine Noxide, a gutderived metabolite linked to risk in some studies), focus on diet and fiber while you discuss L-carnitine with your cardiologist

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Your provider will help you create the right strategy to tackle your concerns from every angle.

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