XiongPHuangXYeNLuQZhangGPengSet alCytotoxicity of metal-based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations
Since SAM is essential for many cellular transmethylation reactions (e.g., epigenetic regulation) (Strauss and Reyes-Dominguez, 2011), and SAH may be an inhibitor of cellular methyltransferases (Sheridan et al., 2016), and finally, the activity of gliotoxin against fungi is revealing even further interactions within biological systems- most recently involving zinc homeostasis (Vicentefranqueira et al., 2018)
For example, among these classes of anti-tumor drugs that can spontaneously partition into RBCs, there are doxorubicin and daunorubicin
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Our study establishes that RSL3 contributes both to thyroid tumor cell DNA damage and concomitant inhibition of DNA damage repair response by limiting the availability of pNPM1 (T199)
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