Histological hallmarks of AxD are the emergence of perivascular Rosenthal fibres consisting of ubiquinated aggregates of GFAP, vimentin, small heat shock proteins -crystallin and Hsp27, and plectin
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Kara Wada is a quadruple board-certified physician in allergy, immunology, and lifestyle medicine, and founder of the Immune Confident Institute
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Measurement of local cerebral blood flow with iodo[ 14 C]antipyrine
it is effective on both pruritus and cholestasis in PFIC, potentially being a disease-modifying intervention