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The majority of hypersensitivity reactions first occurred within 16 weeks of receiving TZP and resolved independently of TE ADA status or titer

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pubmed.ncbi.nlm.nih.gov/41090431/ The clinical program involving the triple agonist retatrutide will uniquely be utilizing a basket trial format A basket trial is a type of clinical trial that evaluates the effect of a single drug across multiple disease states that share a common feature, in this case obesity A basket design nests under a single master protocol multiple subtrials, or baskets, each with its own population, endpoints and analysis plan

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These are typically starter-dose-only plans

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Overcorrection can make the face look puffy and distorted from the rest of the body

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Contamination : One company was found to use nonsterile products, resulting in contamination of the medicine

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