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In preclinical models, co-administration of bimagrumab or dual myostatin/activin A inhibitors with GLP-1R agonists preserves or increases muscle mass while enhancing fat loss, resulting in improved body composition and metabolic outcomes compared with GLP-1R agonist monotherapy [176]
If you prefer to pursue the appeal, continue it in parallel while starting compounded therapy
The combination does have theoretical synergy for body recomposition GLP-1 driving fat loss, IGF-1 LR3 preserving and building lean mass during caloric restriction
Incretin hormones, obesity and gut microbiota
This is depicted in a typical original experiment in Fig
