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Whether co-administration produces any effect greater than either alone in any species

These may include injection site reactions, mild to moderate nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite

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these small, non-coding RNA molecules have a central role in the modulation of platelet activity and represent potential biomarkers to investigate the response to specific anti-platelet treatments (Pordzik et al., 2019)

The idea is to use the lowest dose possible to achieve the desired results while minimizing the risk of any adverse side effects