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Unsurprisingly, not every new AOM asset delivered on those expectations in subsequent phase 2 or phase 3 trials, let alone setting ever more spectacular benchmarks for weight loss, while investors increasingly recognised the importance of a clean tolerability profile alongside compelling efficacy [1]

10.1016/j.fct.2012.10.034 60 MihailoviV.KataniJ.MiiD.StankoviV.MihailoviM.UskokoviA.et al (2014)

Choosing the right one involves thinking not just about initial weight loss but about long-term tolerability, cost sustainability, and availability

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Miller MT

7 Furthermore, a 12-week study in adults with prediabetes demonstrated that daily allulose supplementation (7.5g) improved glucose tolerance and reduced HbA1c levels