IL-23 affects the differentiation of Th17 cells, which may produce IL-17, IL-22, TNF, and IFN effector cytokines
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Our strategy consists in replacing four consecutive amino acids of GLP-1 by three consecutive ureido residues by capitalizing on the structural resemblance of oligourea and -peptide helices
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PROMOTES DETOXIFICATION: Glutathione conjugation (facilitated by glutathione transferase enzymes) helps contribute to detoxification by binding electrophiles that would otherwise bind to proteins or nucleic acids, resulting in cellular damage