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Cynomolgus monkeys were obtained by a certified provider and the study was subjected to the provisions of the United Kingdom Animals Act 1986 and under UK Home Office licence
J Clin Pharm Ther (2022) 47(2):18493
That only manifest after six months, a year, or longer
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Lipid peroxidation preferentially accumulates at lysosomal membranes and precedes lysosome rupture, transcription factor EB (TFEB) activation, and cathepsin-dependent plasma membrane breakdown, thereby positioning lysosomal stress at the center of population-scale death amplification
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